Cerro Largo is playing home against Defensa y Justicia at Estadio Centenario on Fri, Apr 4, 2025, 00:30 UTC. This is Round 1 of the Copa Sudamericana Grp. B.

Predicted lineups are available for the match a few days in advance while the actual lineup will be available about an hour ahead of the match.

This is the first time the teams are playing against each other.